MAPKs are activated in response to stressful stimuli and help regulate apoptosis. There also is desensitization of the mitochondrial permeability transition pore, which can mitigate ischemia−reperfusion injury (Walker et al. 2013). In addition, alcohol may attenuate ischemia−reperfusion injury by activating protein kinase C epsilon (PKCε) (Walker et al. 2013). Activation of PKCε may protect the […]

If you’re someone that gets a severe anxiety before a speech, presentation, social event or any high-stakes situation, you might be considering prescription drugs like Xanax to help solve your problem. Perhaps you’ve heard from a friend/colleague, or read on online forums, about how medications like Xanax helped the performing careers of others or helped […]

If you still want to have a good time and avoid being a party pooper, front-load your drinking for the night (after having something to eat), and slowly taper off from there over the whole evening. Basically, pretend that you’ll be trying to sleep in a loud, well-lit factory that night and prepare accordingly. Fortunately, […]

And, try to continue drinking fluids that are gentle on the digestive system throughout the day (so, water, soda water, and soft sports drinks). Everybody’s different, and therefore the how long do hangovers last length of a hangover will vary from person to person. Typically, hangover symptoms will not last longer than 72 hours, though […]

In rare cases, people with severe rhinophyma might need skin grafts to reconstruct their noses. We believe in you and encourage and support you during addiction treatment. Alcohol can aggravate rosacea flare-ups, thus potentially making rhinophyma more severe. If you have rosacea and struggle with alcohol use, you might be putting yourself at risk of […]